Medical therapy


  • Most of the studies on hormonal treatment have been of poor quality. Long-term data is almost completely lacking.
  • Short-term side effects of hormonal treatment include increased scrotal erythema and pigmentation, and induction of pubic hair and penile growth.
  • The Panel consensus is that endocrine treatment to achieve testicular descent is not recommended.

Using hCG and GnRH

Hormonal therapy using hCG or gonadotropin-releasing hormone (GnRH) is based on the hormonal dependence of testicular descent and has a limited success rate of just 20%. However, hormonal treatment with GnRH before (neo-adjuvant) or after (adjuvant) surgical orchidolysis and orchidopexy may improve future fertility indices.*


Human chorionic gonadotropin therapy
Gonadotropin-releasing hormone therapy
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