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Vesicoureteral reflux or the retrograde flow of urine from the bladder into the ureter, is an anatomic and/or functional disorder with potentially serious consequences such as renal scarring, hypertension, and renal failure. About half the children with VUR have LUTD.
It is possible that VUR is secondary to LUTD and that treatment of LUTD therefore will result in correction of VUR. In contrast, high-grade VUR may affect bladder dynamics, which subsequently leads to LUTD.