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Adolescence is a critical time for urologic monitoring in many of these patients because multiple changes occur in the bladder, including an increase in detrusor leak point pressure, bladder capacity, and maximum detrusor pressure.
These changes can lead to hydronephrosis and worsening renal function if left unchecked
Many patients with poor bladder compliance may need aggressive management with catheterization; antimuscarinic agents; intradetrusor botulinum toxin injections; or even surgical interventions, such as augmentation cystoplasty.
For those patients who previously underwent bladder augmentation, ongoing care and surveillance is also essential.
These individuals are at risk of catheterizable channel stenosis, bladder stones, augment perforation, metabolic abnormalities, vitamin B12 deficiency, and bone demineralization.